RECRUITING

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

We are studying virologic and/or immunologic parameters of HIV infection and other infectious or non-infectious immune deficiency diseases in order to better understand the pathogenesis of HIV. Because of the lack of an adequate animal model it is generally necessary to utilize human peripheral blood cells for studying aspects of either in vivo or in vitro HIV infection. We wish to be able to continue to elucidate many pathogenic aspects of HIV infection in relation to other infectious or non-infectious immune regulation and dysregulation using human peripheral blood mononuclear cells as a model....

Official Title

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

Quick Facts

Study Start:1993-03-09
Study Completion:N/A
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00001281

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 120 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age or older.
  2. * Adequate venous access.
  3. * Have a blood pressure less than or equal to 180/100: pulse rate 50-100, unless a lower pulse rate is considered normal for the volunteer.
  4. * Have adequate blood counts (volunteers living with HIV: hemoglobin greater than or equal to 9.0 g/dL, platelets greater than or equal to 50,000; volunteers living without HIV: hemoglobin greater than or equal to 9.0 g/dL, platelets greater than or equal to 50,000
  5. * Be willing and able to provide written informed consent on screening, comply with study requirements and procedures, and comply with clinic policies
  6. * Willingness to allow blood samples to be used for future studies of HIV infection/pathogenesis, and undergo hepatitis screening
  1. * Pregnant and/or breastfeeding females.
  2. * Active substance abuse or history of prior substance abuse that may interfere with protocol compliance or compromise volunteer safety.

Contacts and Locations

Study Contact

Catherine A Seamon, R.N.
CONTACT
(301) 402-3481
cseamon@cc.nih.gov
Susan L Moir, Ph.D.
CONTACT
(301) 402-4559
sm221a@nih.gov

Principal Investigator

Susan L Moir, Ph.D.
PRINCIPAL_INVESTIGATOR
National Institute of Allergy and Infectious Diseases (NIAID)

Study Locations (Sites)

Washington Hospital Center
Washington D.C., District of Columbia, 20010
United States
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

  • Susan L Moir, Ph.D., PRINCIPAL_INVESTIGATOR, National Institute of Allergy and Infectious Diseases (NIAID)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1993-03-09
Study Completion DateN/A

Study Record Updates

Study Start Date1993-03-09
Study Completion DateN/A

Terms related to this study

Keywords Provided by Researchers

  • Lymphocytes
  • Venipuncture
  • Mononuclear Cells
  • Natural History

Additional Relevant MeSH Terms

  • HIV
  • Immunodeficiencies
  • Infectious Diseases