RECRUITING

Study of the Disease Process of Lymphangioleiomyomatosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Pulmonary lymphangioleiomyomatosis (LAM) is a destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor. This study is designed to determine the disease processes involved at the level of cells and molecules, in order to develop more effective therapy. Researchers intend to identify the proteins and genes that contribute to the process of lung destruction in affected individuals.

Official Title

Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)

Quick Facts

Study Start:1995-12-18
Study Completion:N/A
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00001465

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:16 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Tatyana A Worthy, R.N.
CONTACT
(301) 827-1376
worthyt@mail.nih.gov
Joel Moss, M.D.
CONTACT
(301) 496-1597
mossj@nhlbi.nih.gov

Principal Investigator

Joel Moss, M.D.
PRINCIPAL_INVESTIGATOR
National Heart, Lung, and Blood Institute (NHLBI)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

  • Joel Moss, M.D., PRINCIPAL_INVESTIGATOR, National Heart, Lung, and Blood Institute (NHLBI)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1995-12-18
Study Completion DateN/A

Study Record Updates

Study Start Date1995-12-18
Study Completion DateN/A

Terms related to this study

Keywords Provided by Researchers

  • Smooth Muscle Proliferation
  • Bronchoscopy
  • Female
  • Pneumothorax
  • Tuberous Sclerosis
  • Natural History

Additional Relevant MeSH Terms

  • Lung Disease
  • Pneumothorax
  • Tuberous Sclerosis
  • Lymphangioleiomyomatosis