RECRUITING

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to identify and confirm new blood and tissue markers for prognosis and tumor hypoxia. Tumor hypoxia, or the condition of low oxygen in the tumor, has been shown to increase the risk of tumor spread and enhance tumor resistance to the standard treatment of radiation and chemotherapy in head and neck and lung cancers. We have recently identified several proteins or markers in the blood and in tumors (including osteopontin, lysyl oxidase, macrophage inhibiting factor and proteomic technology) in the laboratory that may be able to identify tumors with low oxygen levels or more aggressive behaving tumors.

Official Title

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Quick Facts

Study Start:1998-09-01
Study Completion:2025-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00568490

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Histologically confirmed squamous cell carcinoma of the head and neck sites or non-small cell lung cancer, or relatives of patients with histologically confirmed squamous cell carcinoma of the head and neck.
  2. * Able to sign a Stanford IRB approved consent form
  1. * Refuse or unable to sign an IRB approved consent form.
  2. * Refuse to be contacted in the future for follow up.

Contacts and Locations

Study Contact

Eyiwunmi Laseinde
CONTACT
Rad-onc-ccto@lists.stanford.edu

Principal Investigator

Quynh-Thu Le
PRINCIPAL_INVESTIGATOR
Stanford University

Study Locations (Sites)

Stanford University School of Medicine
Stanford, California, 94305
United States

Collaborators and Investigators

Sponsor: Stanford University

  • Quynh-Thu Le, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1998-09-01
Study Completion Date2025-04-30

Study Record Updates

Study Start Date1998-09-01
Study Completion Date2025-04-30

Terms related to this study

Additional Relevant MeSH Terms

  • Head and Neck Cancer
  • Lung Cancer
  • Lip Cancer
  • Lip Neoplasms
  • Head and Neck Cancers