RECRUITING

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The researchers think that the use of advanced MR imaging may help people with this disease, because it may better predict areas within a malignant glioma (brain tumor) that are at a high risk of recurring. WeThe reserchers are doing this study to see whether this advanced imaging is a safe treatment that causes few or mild side effects in people with brain tumors.

Official Title

Using Advanced MR Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans: A Pilot Study, and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

Quick Facts

Study Start:2009-03
Study Completion:2025-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00870129

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Suspected or Histopathologically proven diagnosis of high grade or low glioma or tumor is suspected to harbor an isocitrate dehydrogenase (IDH) mutation
  2. * May undergo radiation therapy
  3. * Patient and/or guardian is able to provide written informed consent prior to study registration
  4. * Age ≥ 18 years old
  1. * Extreme claustrophobia that precludes MRI scan
  2. * Known allergic reaction to Gd-DTPA
  3. * Any contraindication to gadolinium intravenous contrast as per standard Department of Radiology contrast guidelines
  4. * Any absolute contraindication to MRI (e.g., pacemaker, aneurysm clip, tissue expander).
  5. * Pregnant or nursing female
  6. * Unable to cooperate for MRI and/or radiation therapy planning

Contacts and Locations

Study Contact

Robert Young, MD
CONTACT
212-639-8196
Sunitha Thakur, PhD
CONTACT
646-608-8262

Principal Investigator

Robert Young, MD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Cancer Center
New York, New York, 10065
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Robert Young, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2009-03
Study Completion Date2025-09

Study Record Updates

Study Start Date2009-03
Study Completion Date2025-09

Terms related to this study

Keywords Provided by Researchers

  • brain tumor
  • radiation
  • MRI
  • 09-009

Additional Relevant MeSH Terms

  • Brain Cancer
  • Glioma