RECRUITING

Pancreatic Cancer Genetics

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.

Official Title

Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients

Quick Facts

Study Start:2008-01
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01102569

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients diagnosed with pancreatic cancer.
  2. * Patients are of Ashkenazi Jewish descent.
  3. * Patients have been Columbia Pancreatic Cancer Prevention Program Registry and Tissue Bank for High-Risk Individuals (IRB-AAAA6154).
  1. * Inability to provide informed consent.
  2. * Under the age of 18 years old.

Contacts and Locations

Study Contact

Fay Kastrinos, MD
CONTACT
212-305-1021
fk18@columbia.edu
Vilma Rosario
CONTACT
212-305-6033
vr2222@columbia.edu

Principal Investigator

Fay Kastrinos, MD
PRINCIPAL_INVESTIGATOR
Columbia University

Study Locations (Sites)

Columbia University Medical Center
New York, New York, 10032
United States

Collaborators and Investigators

Sponsor: Columbia University

  • Fay Kastrinos, MD, PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2008-01
Study Completion Date2026-12

Study Record Updates

Study Start Date2008-01
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Hereditary pancreatic cancer
  • Breast and Ovarian Cancer Syndrome
  • BRCA1/2
  • Ashkenazi Jewish patients

Additional Relevant MeSH Terms

  • Pancreatic Cancer