RECRUITING

National Eye Institute Biorepository for Retinal Diseases

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: \- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database. Objectives: \- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies. Eligibility: * Individuals at least 2 years of age with different types of eye disease. * Healthy volunteers with no history of eye disease. Design: * Participants may be recruited from National Eye Institute studies or may be referred from other sources. * Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease. * Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample. * Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database. * No treatment will be provided as part of this study.

Official Title

NEI Intramural Biorepository for Retinal Diseases

Quick Facts

Study Start:2012-06-18
Study Completion:N/A
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01496625

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:2 Years to 120 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children.
  2. * Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected control suitable for comparison to participants with various retinal diseases, particularly AMD and diabetic retinopathy (taking into account matching factors such as age and past ocular history).
  1. * Are unable or unwilling to give informed consent that includes collection and study of at least one peripheral blood sample.
  2. * Are unable or unwilling to give informed consent that includes use of NIH medical records and clinical samples for research.
  3. * Have a systemic disease that compromises the ability to provide adequate ophthalmologic examination or treatment.

Contacts and Locations

Study Contact

Sheena Jose
CONTACT
(301) 402-7635
sheena.jose@nih.gov
Tiarnan DL Keenan, M.D.
CONTACT
(301) 451-6330
tiarnan.keenan@nih.gov

Principal Investigator

Tiarnan DL Keenan, M.D.
PRINCIPAL_INVESTIGATOR
National Eye Institute (NEI)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Eye Institute (NEI)

  • Tiarnan DL Keenan, M.D., PRINCIPAL_INVESTIGATOR, National Eye Institute (NEI)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2012-06-18
Study Completion DateN/A

Study Record Updates

Study Start Date2012-06-18
Study Completion DateN/A

Terms related to this study

Keywords Provided by Researchers

  • Biological Specimens
  • Retinal Disease
  • Diabetic Retinopathy
  • Phenotype-Genotype correlation
  • Age-Related Macular Degeneration (AMD)
  • Natural History
  • AMD
  • Healthy Volunteer
  • HV

Additional Relevant MeSH Terms

  • Age-Related Macular Degeneration
  • Diabetic Retinopathy
  • Von Hippel-Lindau Syndrome
  • Retinal Disease
  • Retinal Vein Occlusion