RECRUITING

Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Persons without a spleen are susceptible to potentially lethal infections from certain bacteria, with pneumococcus being the most prevalent. Vaccines are provided to help protect against these infections, though they do not so with certainty. Trauma patients who sustain an injury to their spleen currently have three treatment options available for the treating surgeon - nonoperative management, embolization, or removal of the spleen. The purpose of this study is to investigate the antibody response to pneumococcal vaccine in patients undergoing these modes of therapy.

Official Title

Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients

Quick Facts

Study Start:2014-12
Study Completion:2025-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02232191

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult trauma patients (aged 18 to 65 years old) sustaining a splenic injury.
  1. * Ages less than 18 and greater than 65
  2. * Initial planned nonoperative management patient who subsequently undergoes embolization or splenectomy will be withdrawn from the study.

Contacts and Locations

Study Contact

David V Shatz, MD
CONTACT
916-734-5535
dvshatz@ucdavis.edu
Anthony Calabro, PhD
CONTACT
916-734-4365
arcalabro@ucdavis.edu

Principal Investigator

David Shatz, MD
PRINCIPAL_INVESTIGATOR
University of California, Davis

Study Locations (Sites)

University of California, Davis Medical Center
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

  • David Shatz, MD, PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2014-12
Study Completion Date2025-07

Study Record Updates

Study Start Date2014-12
Study Completion Date2025-07

Terms related to this study

Additional Relevant MeSH Terms

  • Asplenia