RECRUITING

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the rapid onset obesity in these children. The investigators would like to study the metabolic phenotype of these children to understand the disturbances in energy balance that lead to the rapid onset obesity.

Official Title

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Quick Facts

Study Start:2015-11
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02602769

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:2 Years to 20 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Children with ROHHAD syndrome
  1. * Children with known genetic causes of obesity

Contacts and Locations

Study Contact

Vidhu Thaker, MD
CONTACT
2128515315
vvt2114@cumc.columbia.edu

Principal Investigator

Vidhu Thaker, MD
PRINCIPAL_INVESTIGATOR
Columbia University

Study Locations (Sites)

Boston Children's Hospital
Boston, New York, 02115
United States
Columbia University Irving Medical Center
New York, New York, 10032
United States

Collaborators and Investigators

Sponsor: Columbia University

  • Vidhu Thaker, MD, PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2015-11
Study Completion Date2025-12

Study Record Updates

Study Start Date2015-11
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Hypoventilation syndrome
  • Hypothalamic dysfunction
  • Autonomic dysregulation
  • Rapid onsey obesity

Additional Relevant MeSH Terms

  • Childhood Obesity
  • Morbid Obesity