RECRUITING

Study of Food Aversion in Patients With Anorexia Nervosa

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Conditions

Anorexia Nervosapsychopathologytreatmentepoxide hydrolasespolyunsaturated fatty acidseicosanoids

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls. This study determines how heritable and biochemical factors influence food metabolism in anorexia nervosa in order to develop more effective treatment strategies.

Official Title

Solving EPHX2 and Polyunsaturated Fatty Acid Interactions in Anorexia Nervosa

Quick Facts

Study Start:2016-11-10
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03100656

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 55 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ill AN subjects will meet current Diagnostic and Statistical Manual of Mental Disorders (DSM V) diagnosis of AN, body mass index (BMI) between 11 kg/m² and 17.5 kg/m², or BMI \> 17.5 kg/m² with active eating disorder symptoms.
  2. * Recovered AN must meet the following criteria at time of study entry: 1) Current or past DSM V diagnosis of AN; 2) BMI between 18.5 kg/m2 and 30 kg/m2; 3) Having maintained a BMI of \>18.5 for at least one year.
  3. * Control must be healthy adolescent or woman negative on our screen for AN, other Axis I psychiatric illnesses, and having maintained a BMI of between 18.5-30 kg/m² since the age of 18.
  1. * Exclusion criteria for AN and control subjects include: Organic brain syndrome, schizophrenia and schizoaffective disorder, untreated thyroid disease, renal disease, hepatic disease, and the regular use of fish-oil containing supplements within the last three months of the study. All pregnant and lactating individuals will be excluded.

Contacts and Locations

Study Contact

Pei-an (Betty) Shih, MPM, PhD
CONTACT
(858) 534-0828
eatingdisorderresearch@ucsd.edu
Nhien Nguyen, MS
CONTACT
n7nguyen@ucsd.edu

Principal Investigator

Pei-an (Betty) Shih, MPM, PhD
PRINCIPAL_INVESTIGATOR
University of California, San Diego

Study Locations (Sites)

UC San Diego Altman Clinical and Translational Research Institute
La Jolla, California, 92037
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

  • Pei-an (Betty) Shih, MPM, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-11-10
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2016-11-10
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • psychopathology
  • treatment
  • epoxide hydrolases
  • polyunsaturated fatty acids
  • eicosanoids

Additional Relevant MeSH Terms

  • Anorexia Nervosa