RECRUITING

Early Rheumatoid Arthritis Lung Disease Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.

Official Title

Early Rheumatoid Arthritis Lung Disease Study

Quick Facts

Study Start:2017-03-31
Study Completion:2029-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03192267

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:19 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 19-90 years of age
  2. * Able to give informed consent
  3. * Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years
  1. * Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
  2. * Pregnant

Contacts and Locations

Study Contact

Aimee B Schreiner, MS
CONTACT
402-559-4873
aischreiner@unmc.edu
Bridget Kramer, RN
CONTACT
402-559-7288
bridget.kramer@unmc.edu

Principal Investigator

Tina D Mahajan, MD
STUDY_CHAIR
University of Nebraska
Bryant R England, MD
PRINCIPAL_INVESTIGATOR
University of Nebraska

Study Locations (Sites)

University of Nebraska Medical Center
Omaha, Nebraska, 68198
United States

Collaborators and Investigators

Sponsor: University of Nebraska

  • Tina D Mahajan, MD, STUDY_CHAIR, University of Nebraska
  • Bryant R England, MD, PRINCIPAL_INVESTIGATOR, University of Nebraska

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-03-31
Study Completion Date2029-03

Study Record Updates

Study Start Date2017-03-31
Study Completion Date2029-03

Terms related to this study

Keywords Provided by Researchers

  • newly diagnosed rheumatoid arthritis
  • lung disease

Additional Relevant MeSH Terms

  • Rheumatoid Arthritis