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Mucosal and Microbiota Changes During Acute Campylobacteriosis

Description

Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.

Study Overview

Study Details

Study overview

Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.

Mucosal and Microbiota Changes During Acute Campylobacteriosis

Mucosal and Microbiota Changes During Acute Campylobacteriosis

Condition
Irritable Bowel Syndrome
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic, Rochester, Minnesota, United States, 55902

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * No abdominal surgery (except appendectomy and cholecystectomy)
  • * Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter
  • * History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease.
  • * History of gastroenteritis in six months prior to Campylobacter enteritis
  • * Pregnancy

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Madhusudan Grover, MBBS, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2026-06