RECRUITING

LVAD Conditioning for Cardiac Recovery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the heart. Multiple previous studies have shown that interventions like this may improve heart function and give patients the opportunity for a better quality of life.

Official Title

Sequential Left Ventricular Assist Device (LVAD) Unloading and Conditioning to Induce Sustained Cardiac Recovery

Quick Facts

Study Start:2017-06-23
Study Completion:2028-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03238690

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosed with heart failure undergoing LVAD implantation as a bridge to transplant
  2. * Enrolled in the Effects of Mechanical Unloading on Myocardial Function and Structure study (IRB 30622)
  1. * Neither the subject nor the subject's representative is willing to provide written consent for participation
  2. * Subjects with adverse events leading to hospitalization during the optimum unloading phase are excluded from participation in the controlled reloading phase

Contacts and Locations

Study Contact

John Kirk
CONTACT
801-585-2944
john.kirk@hsc.utah.edu

Principal Investigator

Stavros Drakos, MD
PRINCIPAL_INVESTIGATOR
University of Utah

Study Locations (Sites)

University of Utah
Salt Lake City, Utah, 84112
United States

Collaborators and Investigators

Sponsor: STAVROS G DRAKOS

  • Stavros Drakos, MD, PRINCIPAL_INVESTIGATOR, University of Utah

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-06-23
Study Completion Date2028-06-30

Study Record Updates

Study Start Date2017-06-23
Study Completion Date2028-06-30

Terms related to this study

Keywords Provided by Researchers

  • LVAD
  • Cardiac Recovery

Additional Relevant MeSH Terms

  • Heart Failure