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Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

Description

Einstein Medical Center in Philadelphia serves a diverse group of the patient population. The majority of patients have a diverse cultural background, low literacy, and poor social-economic status. Medication adherence for chronic medical problems is in a range of 40-70%. Medication adherence among patients on oral anti-cancer therapy is not studied in detail. The main objective is to study medication adherence to oral anticancer agents in patients with low literacy and poor socio-economic status.

Conditions

Cancer
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Related Conditions:

Cancer

Study Overview

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Study Details

Study overview

Einstein Medical Center in Philadelphia serves a diverse group of the patient population. The majority of patients have a diverse cultural background, low literacy, and poor social-economic status. Medication adherence for chronic medical problems is in a range of 40-70%. Medication adherence among patients on oral anti-cancer therapy is not studied in detail. The main objective is to study medication adherence to oral anticancer agents in patients with low literacy and poor socio-economic status.

A Randomized, Controlled Trial to Assess Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients in a Socioeconomically Disadvantaged Community

Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, United States, 19141

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * All patients on oral chemotherapeutic agents
  • * Clinical diagnosis of stage IV breast cancer
  • * Clinical diagnosis of stage III and IV colorectal cancer (not receiving concurrent radiation therapy)
  • * Clinical diagnosis of stage IV non-small cell lung cancer
  • * Clinical diagnosis of stage IV renal cell carcinoma
  • * Clinical diagnosis of stage IV ovarian carcinoma
  • * Clinical diagnosis of multiple myeloma
  • * Clinical diagnosis of chronic myelogenous leukemia on TKI
  • * Clinical diagnosis of myelodysplastic syndrome on Lenalidomide
  • * Adjuvant treatment for Gastro Intestinal Stromal Tumor
  • * Clinical diagnosis of chronic Lymphocytic Leukemia
  • * Clinical diagnosis of metastatic Prostate cancer
  • * Clinical diagnosis of hepatocellular Carcinoma
  • * Clinical diagnosis of stage IV Melanoma
  • * Clinical diagnosis of myelofibrosis/myeloproliferative neoplasms
  • * Age \>18 years
  • * ECOG Performance Status \<3
  • * ECOG Performance Status of 3 and above
  • * Concurrent chemo radiation
  • * Non-English speaker
  • * Clinical diagnosis of dementia, or otherwise unable to give informed consent.
  • * History of non-compliance (defined as the history of 2 or more missed appointments in the clinic).
  • * Pregnant patients
  • * Nursing Home Patients
  • * Incarcerated

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Thomas Jefferson University,

Claudia M Dourado, MD, PRINCIPAL_INVESTIGATOR, Thomas Jefferson University

Study Record Dates

2025-12-20