COMPLETED

COPD-Related Physiology and the Brain

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structural brain abnormalities and cognitive dysfunction early in the course of COPD. The project will generate information to ultimately inform the development of interventions to delay or prevent cognitive dysfunction.

Official Title

Determinants of Altered Brain Structure and Function in Smokers With COPD-Related Lung Pathophysiology

Quick Facts

Study Start:2017-05-01
Study Completion:2025-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT03269721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:30 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Karin F Hoth, PhD
PRINCIPAL_INVESTIGATOR
University of Iowa Department of Psychiatry

Study Locations (Sites)

University of Iowa
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: Karin Hoth

  • Karin F Hoth, PhD, PRINCIPAL_INVESTIGATOR, University of Iowa Department of Psychiatry

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-05-01
Study Completion Date2025-04-30

Study Record Updates

Study Start Date2017-05-01
Study Completion Date2025-04-30

Terms related to this study

Keywords Provided by Researchers

  • Cognition
  • Pulmonary
  • COPD
  • Lung

Additional Relevant MeSH Terms

  • Pulmonary Disease, Chronic Obstructive (COPD)
  • Cognitive Impairment