RECRUITING

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.

Official Title

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Quick Facts

Study Start:2017-03-13
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03419260

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:1 Month to 18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Care in the Children's Hospital of Philadelphia Pediatric ICU.
  2. 2. Clinically indicated continuous EEG monitoring.
  3. 3. Age \> 1 month to 18 years.
  1. 1. Admitted for Phase 2 (intracranial) EEG monitoring.
  2. 2. Intensivist expects to discontinue technological support in the next two days given underlying medical or neurological problems.

Contacts and Locations

Study Contact

Nicholas S Abend, MD
CONTACT
215-590-1719
abend@chop.edu

Principal Investigator

Nicholas S Abend, MD
PRINCIPAL_INVESTIGATOR
Children's Hospital of Philadelphia

Study Locations (Sites)

Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: Children's Hospital of Philadelphia

  • Nicholas S Abend, MD, PRINCIPAL_INVESTIGATOR, Children's Hospital of Philadelphia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-03-13
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2017-03-13
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • seizures
  • status epilepticus
  • EEG monitoring

Additional Relevant MeSH Terms

  • Seizures