RECRUITING

DXA Study of Precision and Reliability

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to assess precision of the GE Lunar iDXA, Hologic Horizon W DXA scanner, and the Stratec peripheral quantitative computed tomography (pQCT) scanner. Aim 1: To assess standard deviation (SD) and coefficient of variation (CV) of testing bone mineral, bone geometry, and soft tissues in inanimate objects and adults. Tests on adults will be structured to assess: 1. Within- and between-day variability of testing 2. Within- and between-technician variability of testing 3. Variability due to positioning and post-scan processing 4. Variability due to different DXA scanning equipment Aim 2: To assess the least significant change (LSC) for testing bone mineral and soft tissues in adults. Aim 3: To assess strengths and limitations of DXA and pQCT testing, including sensitivity to movement, rate of re-rescanning, etc. which are crucial components for demonstrating feasibility in grant applications. Aim 4: To construct a database of DXA and pQCT test results and quality control procedures, showing our laboratory's quality control level.

Official Title

Precision and Reliability of Dual X-ray Absorptiometry (DXA) Testing

Quick Facts

Study Start:2008-06-16
Study Completion:2028-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03621306

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. 1. for females, being pregnant
  2. 2. Having had X-ray procedures using contrast material in the previous 3 days
  3. 3. Having medical devices that interfere with scan accuracy
  4. 4. Wearing external metal objects that cannot be removed
  5. 5. Having internal metal objects
  6. 6. Body mass of \> 450 lbs.
  7. 7. Having ostomies

Contacts and Locations

Study Contact

Mary Jane De Souza, PhD
CONTACT
814-863-0045
mjd34@psu.edu
Nicole Strock, MS
CONTACT
814-863-4488
nca11@psu.edu

Principal Investigator

Mary Jane De Souza, PhD
PRINCIPAL_INVESTIGATOR
Penn State

Study Locations (Sites)

Women's Health and Exercise Laboratories, The Pennsylvania State University
University Park, Pennsylvania, 16802
United States

Collaborators and Investigators

Sponsor: Penn State University

  • Mary Jane De Souza, PhD, PRINCIPAL_INVESTIGATOR, Penn State

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2008-06-16
Study Completion Date2028-08-31

Study Record Updates

Study Start Date2008-06-16
Study Completion Date2028-08-31

Terms related to this study

Additional Relevant MeSH Terms

  • Bone and Bones
  • Body Composition