RECRUITING

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https://www.alz.life/) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.

Official Title

An Observational Trial of Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Quick Facts

Study Start:2018-01-01
Study Completion:2029-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03657745

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Alzheimer's disease
  2. * Cognitive Impairment
  1. * any previously noted epileptic seizures, including febrile seizures.
  2. * any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.

Contacts and Locations

Study Contact

Andrey Vyshedskiy, Ph.D.
CONTACT
(617) 433-7724
vysha@bu.edu

Study Locations (Sites)

Andrey Vyshedskiy
Miami, Florida, 33156
United States

Collaborators and Investigators

Sponsor: Alzheimer's Light LLC

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-01-01
Study Completion Date2029-12-31

Study Record Updates

Study Start Date2018-01-01
Study Completion Date2029-12-31

Terms related to this study

Keywords Provided by Researchers

  • Alzheimer Disease
  • Alzheimer's
  • Dementia

Additional Relevant MeSH Terms

  • Alzheimer Disease
  • Mild Cognitive Impairment
  • Dementia
  • Cognition Disorders in Old Age
  • Cognitive Decline
  • Cognitive Deterioration