RECRUITING

Intraoperative OCT Guidance of Intraocular Surgery II

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical visualization.

Official Title

Intraoperative OCT Guidance of Intraocular Surger

Quick Facts

Study Start:2018-09-30
Study Completion:2025-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03713268

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:4 Weeks
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Healthy controls: Healthy eyes without known disease: refractive error including myopia and non-significant cataract is allowed. For selected testing pseudophakia is allowed.
  2. 2. Surgeons as research subjects: Adult (≥18 years old)
  3. 3. Surgical patients (vitreoretinal surgery): Patients undergoing examination under anesthesia or surgery for vitreoretinal diseases
  4. 4. Surgical patients (anterior segment surgery-glaucoma, ocular surface or strabismus requiring extraocular muscle surgery): Include both adults and children. Patient undergoing primary, elective minimally invasive glaucoma surgery, ocular surface surgery, or strabismus surgery.
  1. 1. Healthy controls: Any ocular disease that restricts the ability to perform OCT scanning. Conflict of interest with investigators/study personnel, e.g. a student in the lab of an investigator.
  2. 2. Surgeons as research subjects: no specific exclusion criteria.
  3. 3. Surgical patients (vitreoretinal surgery): Neonates (\< 4 weeks of age) and patients with any ocular disease that restricts the ability to perform OCT scanning.
  4. 4. Surgical patients (anterior segment surgery-corneal and cataract diseases): Pediatric patients: The cornea and cataract surgery studies will be restricted to adults (≥ 18 years). Children do not have cataract surgery typically by residents and therefore would not fit our study design. Similarly pediatric corneal transplants are very rare.

Contacts and Locations

Study Contact

Neeru Sarin, MBBS
CONTACT
919-668-5341
neeru.sarin@duke.edu
Michelle N McCall, MCAPM, BA
CONTACT
919-684-0554
michelle.mccall@duke.edu

Principal Investigator

Cynthia A Toth, MD
PRINCIPAL_INVESTIGATOR
Duke University

Study Locations (Sites)

Duke University Eye Center
Durham, North Carolina, 27710
United States

Collaborators and Investigators

Sponsor: Duke University

  • Cynthia A Toth, MD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-09-30
Study Completion Date2025-05-31

Study Record Updates

Study Start Date2018-09-30
Study Completion Date2025-05-31

Terms related to this study

Keywords Provided by Researchers

  • Microscope Integrated optical coherence tomography
  • MIOCT
  • OCT Angiography
  • OCTA

Additional Relevant MeSH Terms

  • Macular Holes
  • Epiretinal Membrane
  • Diabetic Retinopathy
  • Retinal Detachment
  • Retinal Disease
  • Preretinal Fibrosis
  • Cataract
  • Ocular Tumor
  • Strabismus
  • Healthy