RECRUITING

Markers of Osteoporosis in Cystic Fibrosis

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Main Study Up to 100 subjects, both non-CF volunteers and Cystic Fibrosis (CF) patients, will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. Denosumab (Prolia) Sub study Approximately 10 adult subjects with CF who participated in the main study and have results indicating bone disease will receive treatment with Denosumab for up to 5 years. They will be asked to return annually for repeat DEXA scans, micro CT, and blood collection.

Official Title

Markers of Osteoporosis in Cystic Fibrosis

Quick Facts

Study Start:2021-09-02
Study Completion:2027-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03921060

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Must have CF diagnosis confirmed by sweat test or genotype analysis
  2. * Subjects (and parents/legal guardians as applicable) must have the ability to read and write in English
  1. * No CF diagnosis
  2. * Men or women without osteoporosis
  3. * Less than 18 years of age
  4. * Unwilling to return annually for study visits for up to 5 years
  5. * Unwilling and/or medically unable to take denosumab

Contacts and Locations

Study Contact

Ashley Keller
CONTACT
2146482817
ashley.keller@utsouthwestern.edu

Study Locations (Sites)

UT Southwestern Medical Center
Dallas, Texas, 75390
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-02
Study Completion Date2027-07

Study Record Updates

Study Start Date2021-09-02
Study Completion Date2027-07

Terms related to this study

Additional Relevant MeSH Terms

  • Cystic Fibrosis