ACTIVE_NOT_RECRUITING

Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI). Secondarily, the project aims to identify blood-based brain biomarkers (BBBM) associated with sleep in Veterans. Specific Aim 1. Determine the effect of MBLT on sleep quality in Veterans (primary outcome). Specific Aim 2. Determine the effect of MBLT on downstream effectors of improved sleep, including cognition, mood, and quality of life measures in Veterans (exploratory outcomes). Specific Aim 3. Determine the effect of MBLT on levels of specific BBBM related to sleep, and whether changes in specific BBBM predict response to MBLT (secondary outcome). This study can now be completed 100% remotely.

Official Title

Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans

Quick Facts

Study Start:2019-08-01
Study Completion:2025-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT03968874

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 88 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Veteran
  2. * English-speaking
  3. * Accessible by phone
  1. * Decisional impairment
  2. * Macular degeneration
  3. * Bipolar disorder
  4. * Shift work
  5. * Currently using lightbox or negative ion generator

Contacts and Locations

Principal Investigator

Miranda Lim, MD, PhD
PRINCIPAL_INVESTIGATOR
Portland VA

Study Locations (Sites)

Portland VA Medical Center
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Portland VA Medical Center

  • Miranda Lim, MD, PhD, PRINCIPAL_INVESTIGATOR, Portland VA

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-08-01
Study Completion Date2025-12-01

Study Record Updates

Study Start Date2019-08-01
Study Completion Date2025-12-01

Terms related to this study

Keywords Provided by Researchers

  • Veterans

Additional Relevant MeSH Terms

  • Traumatic Brain Injury