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Neural Control of Kidney Blood Flow During Exercise in African American Adults

Description

The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During two visits in the research lab, participants will: * Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

Conditions

Healthy
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Study Overview

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Study Details

Study overview

The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During two visits in the research lab, participants will: * Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

Neurovascular Control of Renal Blood Flow During Exercise in African American Adults

Neural Control of Kidney Blood Flow During Exercise in African American Adults

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Boston

University of Massachusetts Boston, Boston, Massachusetts, United States, 02125

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Self-report as either African American or White racial identity
  • * Born in United States
  • * Both biological parents identify as same racial identity as participant
  • * Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
  • * Fluent in English
  • * Hispanic or Latino
  • * Females who are pregnant or lactating
  • * Cardiovascular or renal disease
  • * Hypertension (blood pressure of more than or equal to 130/80 mmHg)
  • * Diabetes
  • * Obesity (body mass index of more than or equal to 30 kg/m2)
  • * Smoker/Tobacco user
  • * Acute medical conditions
  • * Taking prescribed cardiovascular, antihypertensive, or renal medications

Ages Eligible for Study

18 Years to 35 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Massachusetts, Boston,

Rachel C Drew, PhD, PRINCIPAL_INVESTIGATOR, University of Massachusetts, Boston

Study Record Dates

2025-12