RECRUITING

48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer's Disease

Description

Researchers are trying to determine the frequency of seizures and epilepsy in patients with Early-onset Alzheimer's disease (EOAD) using a 48-hour computer assisted ambulatory electroencephalogram.

Conditions

Early Onset Alzheimer Disease
Talk to us

Related Conditions:

Early Onset Alzheimer Disease

Study Overview

On this page

Study Details

Study overview

Researchers are trying to determine the frequency of seizures and epilepsy in patients with Early-onset Alzheimer's disease (EOAD) using a 48-hour computer assisted ambulatory electroencephalogram.

A Prospective Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer's Disease

48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer's Disease

Condition
Early Onset Alzheimer Disease
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Mayo Clinic in Florida, Jacksonville, Florida, United States, 32224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Meets core clinical criteria for non-AD dementia.
  • * Two or more first degree relatives with a history of EOAD suggestive of autosomal dominant transmission, unless known pathogenic mutations in APP, PSEN1, PSEN2 have been excluded.
  • * Known mutation in an ADAD gene (APP, PSEN1, PSEN2) or other autosomal dominant genes associated with other neurodegenerative disorders.
  • * MRI scans with evidence of infection or focal lesions, cortical strokes, multiple lacunes (single lacune is allowable unless it meets criteria for strategic lacune affecting cognition)
  • * Any significant systemic illness or unstable medical condition, which could lead to difficulty complying with the protocol (at the discretion of the Site PI)
  • * Medical history of a brain disorder other than the disorder causing dementia except for headache.
  • * Deemed ineligible by the Site PI for any other reason.

Ages Eligible for Study

40 Years to 64 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Neill Graff-Radford, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-12