RECRUITING

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: Heart disease is a leading cause of death in the United States. Healthy diet and exercise improve heart health. Some features of where a person lives can lead to stress and decrease chances for exercise. Researchers want to see how these factors may increase the risk of heart disease in women. Objective: To see if there are differences in stress levels between women who live in different parts of Washington, DC. Also, to see how these women use their neighborhoods for exercise. Eligibility: Healthy white or black females ages 19-45 who live in Washington, DC, who have access to a smartphone Design: Participants may stay at the NIH Clinical Center overnight for a 2-day visit. Visit 1 will include: Physical exam Blood tests Electrocardiogram: Electrodes on the participant s skin will measure heart activity. PET/CT scan: Participants will get an injection. They will lie in a machine that takes pictures of the body. Surveys Body size measurements Nutrition consultation Blood vessel tests: This is measured with blood pressure cuffs, a device placed on the participant s fingertip, and a probe placed on the participant s neck. Resting Energy Expenditure: Participants will breathe under a clear hood for 45 minutes. Participants will be followed for about 2 weeks. They will wear a device on the wrist and carry a GPS device. Through a mobile app, they will answer short daily surveys on stress and exercise. Visit 2- Device return Nutritional consultation

Official Title

Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Quick Facts

Study Start:2021-10-20
Study Completion:2025-12-26
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04014348

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:19 Years to 45 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. A healthy self-identified White female (i.e. self-identifies as White or of European descent) or healthy Black female (i.e. self-identifies as Black, African American, or of African descent)
  2. 2. Must be between 19 to 45 years of age
  3. 3. Must not have any chronic health condition (i.e.: cardiovascular, autoimmune, endocrinologic), or active infection
  4. 4. Must be living in Washington, DC
  5. 5. Must have access to a smartphone
  6. 6. Must be able to provide informed consent
  7. 7. Must speak English.
  1. 1. Pregnant or breast feeding
  2. 2. Physically unable to perform physical activity for any reason
  3. 3. Subject had weight changes greater than 20% over the past 3 months
  4. 4. Subject is obese by our measurements (BMI greater than or equal to 35.0 kg/m\^2)
  5. 5. If you have high or low blood pressure requiring medications
  6. 6. Diabetes
  7. 7. History of severe mental illnesses, treated with hospitalization
  8. 8. If you have evidence of active thyroid disease requiring medications
  9. 9. If you are taking medication for chronic non-mental health related illness (ie: cardiovascular, autoimmune, endocrinologic)
  10. 10. If you have food allergies or highly restrictive diets that may prevent your ability to consume a controlled metabolic diet.
  11. 11. If you are a current smoker (tobacco products)

Contacts and Locations

Study Contact

Marie Marah, R.N.
CONTACT
(301) 640-1701
marie.marah@nih.gov
Tiffany M Powell-Wiley, M.D.
CONTACT
(301) 594-3735
powelltm2@mail.nih.gov

Principal Investigator

Tiffany M Powell-Wiley, M.D.
PRINCIPAL_INVESTIGATOR
National Heart, Lung, and Blood Institute (NHLBI)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

  • Tiffany M Powell-Wiley, M.D., PRINCIPAL_INVESTIGATOR, National Heart, Lung, and Blood Institute (NHLBI)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-10-20
Study Completion Date2025-12-26

Study Record Updates

Study Start Date2021-10-20
Study Completion Date2025-12-26

Terms related to this study

Keywords Provided by Researchers

  • Neighborhood Environment
  • Cardiovascular Disease Risk
  • Social Determinants of Health
  • Diagnostic Behavioral study
  • Socio-Economic
  • Natural History

Additional Relevant MeSH Terms

  • Cardiovascular (CV) Risk