RECRUITING

Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate the brain activity associated with motor and non-motor symptoms of movement disorders, including Parkinson's disease (PD) and essential tremor. These movement disorders commonly have significant non-motor features, such as depression, cognitive and memory impairment, decreased attention, speech and language disturbances, and slower processing speeds. The investigators are interested in the brain activity associated with these motor and non-motor symptoms, and propose to investigate changes in brain activity while the investigators perform recordings of the surface and deep structures of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

Official Title

Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

Quick Facts

Study Start:2019-09-01
Study Completion:2026-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04061135

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Eligible for DBS surgery based on multi-disciplinary consensus review
  2. * Have a diagnosis of Parkinson's disease or Essential Tremor
  3. * A minimum of 18 years of age
  4. * Willingness to participate in the paradigms described in the protocol
  1. * Inability to provide full and informed consent
  2. * Are not surgical candidates due to co-morbid conditions or pregnancy
  3. * Have not undergone an adequate trial of conservative medical management
  4. * Have a clinical presentation for which DBS surgery is not indicated
  5. * Are not able to participate in study-related activities

Contacts and Locations

Study Contact

Nicole Bentley, MD
CONTACT
205-975-0011
jbentley@uabmc.edu

Principal Investigator

Nicole Bentley, MD
PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham

Study Locations (Sites)

University of Alabama at Birmingham
Birmingham, Alabama, 35233
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

  • Nicole Bentley, MD, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-09-01
Study Completion Date2026-03-31

Study Record Updates

Study Start Date2019-09-01
Study Completion Date2026-03-31

Terms related to this study

Keywords Provided by Researchers

  • Parkinson's disease

Additional Relevant MeSH Terms

  • Movement Disorders