RECRUITING

Phase 1/1b/2 Study of Oral PMD-026 in Patients with Metastatic Breast Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to test the safety and tolerability of PMD-026 in patients with metastatic breast cancer. PMD-026 is a targeted oral agent designed to kill tumor cells in metastatic breast cancer.

Official Title

Ph 1/1b/2 Multicenter, Open-Label, FIH Dose Esc & Dose Exp Study to Assess Safety and Tolerability of Orally Administered PMD-026 As a Single Agent and in Combination in Patients with Metastatic or Locally Advanced (Inoperable) RSK2+ Breast Cancer

Quick Facts

Study Start:2019-11-14
Study Completion:2026-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04115306

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Phoenix Molecular Designs
CONTACT
8589456456
clinical@phoenixmd.ca
Brian Barnett, MD
CONTACT
clinical@phoenixmd.ca

Study Locations (Sites)

Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234
United States
University of California, Los Angeles (UCLA)
Los Angeles, California, 90095
United States
Moffitt Cancer Center
Tampa, Florida, 33612
United States
Ohio State University
Columbus, Ohio, 43210
United States
South Texas Accelerated Research Therapeutics
San Antonio, Texas, 78229
United States

Collaborators and Investigators

Sponsor: Phoenix Molecular Designs

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-11-14
Study Completion Date2026-03

Study Record Updates

Study Start Date2019-11-14
Study Completion Date2026-03

Terms related to this study

Keywords Provided by Researchers

  • invasive breast cancer
  • PR-negative breast cancer
  • HER2-negative breast cancer
  • Breast cancer
  • Breast malignancy
  • breast malignancies
  • metastatic breast cancer
  • advanced breast cancer
  • solid tumor
  • late stage breast cancer/late-stage breast cancer

Additional Relevant MeSH Terms

  • Metastatic Breast Cancer