RECRUITING

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium. Magnesium sulfate has also proven to be successful in managing pain before and after surgery. However, this drug has primarily been used for pain control in patients undergoing surgery. Patients in the ICU with injuries also need good pain control. Using magnesium may assist in decreasing narcotic (pain reliever) requirements and provide another non-narcotic drug for pain control. The purpose of this study is to test the effectiveness of continuous, intravenous (into or within a vein using a needle) administration of magnesium sulfate for pain control in trauma patients admitted to the adult Intensive Care Unit. This will be compared to intravenous normal saline (salt solution).

Official Title

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

Quick Facts

Study Start:2019-12-07
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04166877

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All trauma patients admitted to an adult intensive care unit
  2. * Signed informed consent
  3. * Hospital or trauma multimodal pain management order set used for pain management
  4. * Ages 18-99
  1. * Admission to the Pediatric Intensive Care Unit.
  2. * Head Abbreviated Injury Score (AIS) of greater than 1
  3. * Known heart failure with reduced ejection fraction (EF \< 40%)
  4. * Renal failure (GFR \< 60)
  5. * Cardiac arrhythmia (except for sinus tachycardia)
  6. * Greater than 5% TBSA burn injuries
  7. * Moderate to severe alcohol withdrawal protocol ordered for patient
  8. * Regular use of opioids in the week prior to injury
  9. * Receiving continuous infusion of opioids
  10. * Patients expected to require general anesthesia between 24 and 48 hours after admission (during study drug administration)
  11. * Patients unable to provide consent is unavailable
  12. * Patients unable to provide a pain score
  13. * Pregnancy
  14. * Prisoners

Contacts and Locations

Study Contact

Christine S Cocanour, MD
CONTACT
9167347330
cscocanour@ucdavis.edu
G J Jurkovich, MD
CONTACT
9167348298
gjjurkovich@ucdavis.edu

Study Locations (Sites)

UC Davis Health
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-12-07
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2019-12-07
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • magnesium sulfate
  • trauma
  • acute pain

Additional Relevant MeSH Terms

  • Trauma
  • Acute Pain