RECRUITING

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.

Official Title

Impact of Decreased Venous Return on Supine Blood Pressure

Quick Facts

Study Start:2020-08-21
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04502225

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients with autonomic failure and with supine hypertension from all races
  2. * Males and females, between 18 to 85 years
  1. * All medical students
  2. * Pregnant women
  3. * High-risk patients (for example: heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)
  4. * History of serious allergies or asthma.

Contacts and Locations

Study Contact

Bonnie K Black, RN
CONTACT
615-343-6862
bonnie.black@vumc.org
Luis E. Okamoto, MD
CONTACT
(615) 936-6119
luis.e.okamoto@vumc.org

Principal Investigator

Italo Biaggioni, MD
PRINCIPAL_INVESTIGATOR
Vanderbilt University Medical Center

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Italo Biaggioni, MD, PRINCIPAL_INVESTIGATOR, Vanderbilt University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-08-21
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2020-08-21
Study Completion Date2026-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Supine Hypertension
  • Autonomic Failure