RECRUITING

Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals

Description

Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke. Thus, the overall purpose of this research project is to examine stroke survivors' capability of learning a novel leg task over 3 visits, 1-2 weeks apart. The capability of learning a new skill is then correlated with the individual's neurological functions (nerve activity and movement coordination) and her/his gait performance (gait speed, gait symmetry, and force production).

Conditions

StrokeMultiple Sclerosis
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Related Conditions:

StrokeMultiple Sclerosis

Study Overview

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Study Details

Study overview

Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke. Thus, the overall purpose of this research project is to examine stroke survivors' capability of learning a novel leg task over 3 visits, 1-2 weeks apart. The capability of learning a new skill is then correlated with the individual's neurological functions (nerve activity and movement coordination) and her/his gait performance (gait speed, gait symmetry, and force production).

Comparison of Motor Skill Acquisition Between Individuals With Neurological Disorders

Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Houston

Texas Woman's University, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy adults have no ongoing neurological, musculoskeletal issues.
  • * Individuals with chronic stroke had medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment.
  • * Individuals have multiple sclerosis disease diagnosed by his/her physician
  • * MRI or CT evidence from the imaging report shown that the stroke and multiple sclerosis disease primarily involve cortical and subcortical regions.
  • * Individuals with chronic stroke have hemiparesis involving the lower extremity.
  • * Individuals with chronic stroke or multiple sclerosis have no passive range of motion limitation in bilateral hips and knees. Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less.
  • * Visual acuity can be corrected by glasses or contact lens to 20/20.
  • * Able to walk independently with/without assistant devices for 10 meters.
  • * Able to maintain standing position without any assistance for more than 30 sec.
  • * Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24.
  • * Pregnant women.
  • * MRI or CT evidence of involvement of the basal ganglia or cerebellum, or evidence of any other brain damage or malignant neoplasm or tumors.
  • * Have any metal implants, cardiac pacemakers, or history of seizures.
  • * Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training.
  • * Any vestibular dysfunction or unstable angina.
  • * Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\*

Ages Eligible for Study

21 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Texas Woman's University,

Shih-Chiao Tseng, PT, PhD, PRINCIPAL_INVESTIGATOR, Texas Woman's University School of Physical Therapy

Study Record Dates

2024-12-31