RECRUITING

Cardiac Rehab Effects in HFpEF

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research in Veterans with heart failure with preserved ejection fraction (HFpEF) will provide new information on the mechanisms determining the patients' exercise intolerance and the efficacy of regular physical activity to improve this shortcoming by alleviating the patients' neurocirculatory abnormalities. Specifically, the investigators will focus on the role of nerves originating in working limb muscles in determining the patients' exercise intolerance and compromised fatigue resistance before and after a chronic exercise intervention. By focusing on a specific mechanism, this project will evaluate the validity of exercise as an alternative treatment strategy with the overall purpose of improving the quality of life of Veterans with HFpEF.

Official Title

Efficacy of Exercise Training in Patients With HFpEF

Quick Facts

Study Start:2022-05-02
Study Completion:2026-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04506606

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * heart failure with preserved ejection fraction
  1. * heart failure with reduced ejection fraction

Contacts and Locations

Study Contact

Misti R Seppi, MBA BS AAS
CONTACT
(801) 582-1565
Misti.Seppi@va.gov

Principal Investigator

Markus Amann, PhD
PRINCIPAL_INVESTIGATOR
VA Salt Lake City Health Care System, Salt Lake City, UT

Study Locations (Sites)

VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, 84148-0001
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Markus Amann, PhD, PRINCIPAL_INVESTIGATOR, VA Salt Lake City Health Care System, Salt Lake City, UT

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-05-02
Study Completion Date2026-09-30

Study Record Updates

Study Start Date2022-05-02
Study Completion Date2026-09-30

Terms related to this study

Additional Relevant MeSH Terms

  • Heart Failure With Preserved Ejection Fraction