RECRUITING

A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning. This hypothesis applies to learning in general, but is especially critical as an avenue for developing earlier assessments and more powerful interventions for children with developmental language disorder (DLD; also known as specific language impairment). Other populations, such as at-risk toddlers, may also benefit from this new approach.

Official Title

A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In Developmental Language Disorder: Production

Quick Facts

Study Start:2022-08-07
Study Completion:2026-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04558541

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:4 Years to 8 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * All children (TD, DLD, DLD + SSD, SSD) will score above 75 on the Nonverbal Scale of the Kaufman Assessment Battery for Children (KABC-II), which is above the Diagnostic and Statistical Manual cut-off for intellectual disability, even considering the standard error of measurement.
  2. * Hearing will be within normal limits
  3. * Oral structures will be within normal limits (Robbins \& Klee, 1987).
  4. * The Childhood Autism Rating Scale (Schopler et al., 2010) and parent report, will be used to rule out autism.
  5. * Children with DLD will score below the cutoff of 87 on the Structured Photographic Expressive Language Test-P2 (SPELT-P2; Dawson et al., 2005) that has demonstrated high diagnostic accuracy for DLD.
  6. * Children with DLD will perform below 80% in their spontaneous production of finite verb morphemes.
  7. * Performance on a nonword repetition task will also support DLD status. Scores below 70% for total phonemes correct across all nonword lengths are greater than 1 SD below the mean for typical children.
  8. * Speech production skills will be measured via the Goldman-Fristoe Test of Articulation-3 (GFTA-3; Goldman \& Fristoe, 2015) and the inconsistency subtest of the Diagnostic Evaluation of Articulation and Phonology (DEAP, Dodd, et al., 2006). Many 4- to 6-year-old children with DLD are expected to perform below expected levels on the GFTA-3; for this study half of the children with DLD will show performance below expected levels and half above a standard score of 85. Children with SSD will show impaired performance on the GFTA-3, but typical performance on grammatically weighted language measures (SPELT-P2 and finite verb morphemes). The DEAP serves as a standardized measure of segmental inconsistency and will provide a post hoc analysis that may be related to sequence pattern variability.
  9. * Peabody Picture Vocabulary Test, 4th ed (Dunn \& Dunn, 1997)
  10. * Expressive Vocabulary Test, 2nd ed (Williams, 1997)
  11. * Verbal and nonverbal memory span.
  12. * Because of the emphasis on English phonological and morpho-syntactic patterns, all participants will be monolingual English learners or report dominant exposure to English from infancy. Exposure to other languages will be documented.
  13. * Hearing impairment
  14. * Intellectual impairment
  15. * Autism
  16. * Significant motor impairment.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Lisa Goffman, PhD
CONTACT
531-355-5038
lisa.goffman@boystown.org
LouAnn Gerken, PhD
CONTACT
gerken@email.arizona.edu

Study Locations (Sites)

University of Arizona
Tucson, Arizona, 85721
United States
Boys Town National Research Hospital
Omaha, Nebraska, 68131
United States

Collaborators and Investigators

Sponsor: Father Flanagan's Boys' Home

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-07
Study Completion Date2026-07-31

Study Record Updates

Study Start Date2022-08-07
Study Completion Date2026-07-31

Terms related to this study

Additional Relevant MeSH Terms

  • Developmental Language Disorder
  • Speech Sound Disorder
  • Specific Language Impairment