RECRUITING

Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury.

Official Title

Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (BioBOOST)

Quick Facts

Study Start:2020-12-20
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04565119

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Enrolled in BOOST-3 (this is an ancillary study to the BOOST-3 trial)
  2. * BOOST-3 participant is enrolled at a BioBOOST site
  3. * Able to maintain initial blood sample within 24 hours of injury
  4. * Provide proxy informed consent
  1. * Profoundly anemic (subjects who are profoundly anemic require blood transfusion)
  2. * Age less than 18 years

Contacts and Locations

Study Contact

Ramon Diaz-Arrastia, MD, PhD
CONTACT
215-662-9732
Ramon.Diaz-Arrastia@pennmedicine.upenn.edu
Cynthia Diaczynsky
CONTACT
cynthia.diaczynsky@pennmedicine.upenn.edu

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48109
United States
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-12-20
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2020-12-20
Study Completion Date2027-12-31

Terms related to this study

Keywords Provided by Researchers

  • Biomarkers

Additional Relevant MeSH Terms

  • TBI (Traumatic Brain Injury)