RECRUITING

Imaging of Solid Tumors Using FAP-2286

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a multi-arm prospective trial that evaluates the ability of a novel imaging radiolabeled agents to detect metastatic cancer in participants with solid tumors using a gallium 68 (68Ga-) or copper 64 (64Cu-) FAP-2286 tracer. FAP-2286 is a peptidomimetic molecule that that binds to Fibroblast Activation Protein (FAP). FAP is a transmembrane protein expressed on cancer-associated fibroblasts, and has been shown to be present on a number of solid tumors.

Official Title

Imaging of Solid Tumors Using FAP-2286

Quick Facts

Study Start:2020-12-14
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04621435

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age \>= 18 years
  2. 2. Histopathologically confirmed solid tumors in one of the following cohorts:
  3. 3. Ability to understand a written informed consent document, and the willingness to sign it.
  1. 1. Unlikely to comply with protocol procedures, restrictions and requirements and judged by the Investigator to be unsuitable for participation.
  2. 2. Known pregnancy.

Contacts and Locations

Study Contact

Maya Aslam
CONTACT
877-827-3222
Maya.Aslam@ucsf.edu

Principal Investigator

Thomas Hope, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: Thomas Hope

  • Thomas Hope, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-12-14
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2020-12-14
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • PET
  • 68Ga-FAP-2286
  • 64Cu-FAP-2286

Additional Relevant MeSH Terms

  • Solid Tumors, Adult
  • Metastatic Cancer