RECRUITING

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The standard of care imaging of prostate cancer metastases recommended by the National Comprehensive Cancer Network (NCCN), CT of the chest/abdomen/pelvis and bone scan, may be suboptimal. PyL is a novel PET tracer designed to detect prostate specific membrane antigen (PSMA) expressed on prostate cancer cells. PyL PET/CT may provide improved evaluation of clinically significant metastases in patients with prostate cancer.

Official Title

2-(3-{1-carboxy-5-[(6-18F-fluoro-pyridine-3-carbonyl)-Amino]-Pentyl}-Ureido)-Pentanedioic Acid (PyL) in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Quick Facts

Study Start:2021-02-01
Study Completion:2022-12-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04700332

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Male ≥ 18 years of age.
  2. 2. Histologically confirmed adenocarcinoma of the prostate
  3. 3. Patients meet one of the follow criteria:
  1. 1. Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.
  2. 2. Patients who cannot undergo PET/CT scanning because of weight limits. PET/CT scanners may not be able to function with patients over 450 pounds.
  3. 3. Change in therapy since standard of care imaging

Contacts and Locations

Study Contact

Beth Thomsen
CONTACT
949-764-4577
clinicalresearch@hoag.org

Principal Investigator

Deborah Fridman, PsyD, RN
STUDY_DIRECTOR
Hoag Memorial Hospital Presbyterian

Study Locations (Sites)

Hoag Memorial Hospital Presbyterian
Irvine, California, 92618
United States

Collaborators and Investigators

Sponsor: Hoag Memorial Hospital Presbyterian

  • Deborah Fridman, PsyD, RN, STUDY_DIRECTOR, Hoag Memorial Hospital Presbyterian

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-02-01
Study Completion Date2022-12-15

Study Record Updates

Study Start Date2021-02-01
Study Completion Date2022-12-15

Terms related to this study

Keywords Provided by Researchers

  • Prostate Cancer
  • DCFPyL PET/CT
  • Staging
  • Biochemical relapse

Additional Relevant MeSH Terms

  • Prostate Cancer