RECRUITING

Investigating Inhibitory Control Networks in Parkinson's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

Official Title

Investigating Inhibitory Control Networks in Parkinson's Disease

Quick Facts

Study Start:2021-04-01
Study Completion:2026-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04735458

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Eligible for surgery based on multi-disciplinary consensus review
  2. * Have a diagnosis of Parkinson's disease or Essential Tremor
  3. * Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
  4. * Willingness to participate in the paradigms described in the protocol
  1. * Inability to provide full and informed consent
  2. * Age younger than 18
  3. * Are not able to participate in study-related activities
  4. * History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure

Contacts and Locations

Study Contact

Nicole Bentley, MD
CONTACT
205-975-0011
jbentley@uabmc.edu

Principal Investigator

Nicole Bentley, MD
PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham

Study Locations (Sites)

University of Alabama at Birmingham
Birmingham, Alabama, 35233
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

  • Nicole Bentley, MD, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-04-01
Study Completion Date2026-03-31

Study Record Updates

Study Start Date2021-04-01
Study Completion Date2026-03-31

Terms related to this study

Additional Relevant MeSH Terms

  • Parkinson Disease