TERMINATED

Dose of Vestibular Rehabilitation for Vestibular Hypofunction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purposes of this research are to 1) utilize virtual reality (VR) to evaluate the exercise dose required to improve symptoms in those with vestibular (dizziness) disorders, 2) compare VR vestibular exercises to standard exercises, and 3) compare exercise performance outcomes to healthy controls without vestibular disorders. Even though more than 35% of those over 40, and \~50% of those who have had concussion have such symptoms, the dose of specific exercises targeted to improve symptoms is not well defined. In this study, the investigators will use a wireless VR device to measure key parameters and response to exercise. Another advantage of the VR device is the ability to control what the individual can see while performing the exercise. In normal daily life, moving objects and distracting backgrounds can make vestibular exercise too uncomfortable to perform. Using these methods, the investigators aim to determine the appropriate type and amount of exercise required for symptom improvement. This study will also compare the effectiveness of performing exercises in the virtual reality environment to standard physical therapy and to healthy persons without history of vestibular disorders. Three categories of vestibular disorders will be investigated with an instrumented and usual therapy group of 1) Unilateral hypofunction, 2) bilateral hypofunction, and 3) post-concussion.

Official Title

Dose of Vestibular Rehabilitation Required for Clinical Improvements in Individuals With Vestibular Hypofunction.

Quick Facts

Study Start:2021-03-22
Study Completion:2024-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:TERMINATED

Study ID

NCT04851184

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 74 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Known or suspected vestibular dysfunction
  2. * Healthy volunteers without dizziness to serve as healthy control subjects
  1. * Previous cerebrovacular accident (stroke)
  2. * Reported neurologic or oculuomotor disease
  3. * Taking of medications that affect the vestibular or oculomotor system.
  4. * Current symptoms of benign paroxysmal positional hypofunction
  5. * Concussion occuring less than 7 days prior to enrollment in this study
  6. * Currently pregnant, or plan to become pregnant during the timeline of the study
  7. * Chronic kidney disease
  8. * COPD
  9. * Known coronary artery disease or cardiomyopathy
  10. * immunocompromised state from a solid organ transplant
  11. * Severe Obesity as defined by BMI of greater than or equal to 40 kg/m2
  12. * Sickle cell disease

Contacts and Locations

Principal Investigator

Karen Goodman, DPT
PRINCIPAL_INVESTIGATOR
The George Washington University

Study Locations (Sites)

The George Washington University, Department of Health, Human Function and Rehabilitation Science
Washington D.C., District of Columbia, 20006
United States

Collaborators and Investigators

Sponsor: George Washington University

  • Karen Goodman, DPT, PRINCIPAL_INVESTIGATOR, The George Washington University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-03-22
Study Completion Date2024-09-01

Study Record Updates

Study Start Date2021-03-22
Study Completion Date2024-09-01

Terms related to this study

Keywords Provided by Researchers

  • gaze stability
  • vestibular hypofunction

Additional Relevant MeSH Terms

  • Vestibular Disorder