COMPLETED

Effects of 100% Orange Juice on Skin Health in Women

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Daily consumption of Orange Juice (OJ) protects skin against UV-induced damages and wrinkling, improves skin barrier function and overall skin health by decreasing oxidative stress, inflammation, and protein glycation. The positive effects of OJ on skin appearance are associated with improvements of the stratum corneum lipidomic and skin microbiome.

Official Title

A Pilot Clinical Trial to Assess the Effects of 100% Orange Juice on Skin Health in Women Using a Randomized Double-Blinded Placebo-Controlled Crossover Design

Quick Facts

Study Start:2023-01-04
Study Completion:2025-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04861623

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:45 Years to 65 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * BMI (18.5-29.9)
  2. * Body weight ≥110 pounds
  3. * Fitzpatrick skin type 2 and 3.
  1. * pregnancy
  2. * breast-feeding
  3. * impaired fasting glucose
  4. * frequent alcohol use
  5. * history of skin cancer
  6. * sunbathing and the use of tanning bed, intake of vitamin/mineral supplements
  7. * habitual high intake of fruits (≥ 2 cups daily)
  8. * intake of medication that might influence the outcome of the study

Contacts and Locations

Study Locations (Sites)

Food Science and Human Nutrition Department at University of Florida
Gainesville, Florida, 32611
United States

Collaborators and Investigators

Sponsor: University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-04
Study Completion Date2025-10-31

Study Record Updates

Study Start Date2023-01-04
Study Completion Date2025-10-31

Terms related to this study

Keywords Provided by Researchers

  • Orange Juice
  • Skin health

Additional Relevant MeSH Terms

  • Skin Health