RECRUITING

Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The loss of movement and walking ability significantly affects quality of life after spinal cord injury. In addition, bladder dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord injury. The overall objective of this study is to demonstrate that epidural stimulation may be a method for improving stepping, standing and bladder function in individuals with spinal cord injury. With the use of epidural stimulation, the investigators propose to investigate how well the participant can stand and walk and how well the participant's bladder can store or hold urine as well as void or empty urine. The results of this study may aid in the development of treatments to help individuals with spinal cord injuries that are unable to stand or walk and have impaired bladder function.

Official Title

Inter-System Closed-Loop Control of Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Quick Facts

Study Start:2022-04-04
Study Completion:2026-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04879862

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. At least 18 years of age
  2. 2. non-progressive SCI
  3. 3. stable medical condition
  4. 4. Inability to stand and step independently
  5. 5. unable to voluntarily move all individual joints of the legs
  6. 6. no current anti-spasticity medication regimen
  7. 7. must not have received botox injections in the prior six months
  8. 8. Bladder dysfunction as a result of SCI
  9. 9. SCI between T1 and T10
  10. 10. no greater than 1 year post injury
  1. 1. ventilator dependent
  2. 2. untreated painful musculoskeletal dysfunction, fracture or pressure sore
  3. 3. untreated psychiatric disorder or ongoing drug abuse
  4. 4. cardiovascular, respiratory, bladder, or renal disease unrelated to SCI
  5. 5. pregnant at the time of enrollment or planning to become pregnant during the time course of the study.

Contacts and Locations

Study Contact

Manpreet Chopra
CONTACT
502-582-7443
manpreet.chopra@louisville.edu

Study Locations (Sites)

Kentucky Spinal Cord Injury Center - University of Louisville
Louisville, Kentucky, 40202
United States

Collaborators and Investigators

Sponsor: Susan Harkema PhD

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-04
Study Completion Date2026-04-01

Study Record Updates

Study Start Date2022-04-04
Study Completion Date2026-04-01

Terms related to this study

Keywords Provided by Researchers

  • locomotion
  • epidural stimulation
  • bladder function

Additional Relevant MeSH Terms

  • Spinal Cord Injuries