ACTIVE_NOT_RECRUITING

Reflex Excitability in Post-stroke Stiff-Knee Gait

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait. We use electrical stimulation of the peripheral nerve innervating the rectus femoris for a well-controlled reflex stimulus. We are investigating whether reflex excitability of the rectus femoris correlates with gait kinematics.

Official Title

Characterization of Abnormal Reflex Couplings Via H-reflex Stimulation

Quick Facts

Study Start:2021-06-11
Study Completion:2026-06-11
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT04947865

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aged at least 18
  2. * Premorbidly independent
  3. * If post-stroke, mild to moderate impairment determined by standard practices per the physical therapist
  4. * Able to continuously walk for 30 minutes
  5. * If post-stroke, reduced knee flexion during walking relative to unimpaired side
  6. * If post-stroke, hemiparesis
  7. * Ability to provide informed consent
  1. * No history of serious lower limb musculoskeletal injury
  2. * No functionally relevant osteoarthritis and weight-bearing restrictions
  3. * No functionally relevant polyneuropathy
  4. * No functionally relevant cognitive impairment
  5. * No functionally relevant vision impairment

Contacts and Locations

Principal Investigator

James S Sulzer
PRINCIPAL_INVESTIGATOR
Case Western Reserve University

Study Locations (Sites)

MetroHealth Medical Center
Cleveland, Ohio, 44109
United States

Collaborators and Investigators

Sponsor: MetroHealth Medical Center

  • James S Sulzer, PRINCIPAL_INVESTIGATOR, Case Western Reserve University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-06-11
Study Completion Date2026-06-11

Study Record Updates

Study Start Date2021-06-11
Study Completion Date2026-06-11

Terms related to this study

Additional Relevant MeSH Terms

  • Stroke
  • Chronic Stroke
  • Gait, Hemiplegic
  • Gait, Spastic
  • Gait Disorder, Sensorimotor
  • Gait Disorders, Neurologic
  • Walking, Difficulty