RECRUITING

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research is to examine the effects of two different exercise training regimens for managing depression and improving other health indicators among persons with multiple sclerosis (MS). The project will enroll persons with MS and major depressive disorder (MDD) between 18 and 64 years of age. The investigators will enroll a total of 146 participants. This is a Phase-II trial that compares the efficacy of an exercise training program (POWER-MS) compared with a stretching program (FLEX-MS) for immediate and sustained reductions in the severity of depression among persons with MS who have MDD.

Official Title

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

Quick Facts

Study Start:2023-04-01
Study Completion:2025-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05051618

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Robert W Motl, PhD
CONTACT
205-975-1306
robmotl@uic.edu

Principal Investigator

Robert W Motl, PhD
PRINCIPAL_INVESTIGATOR
University of Illinois Chicago

Study Locations (Sites)

University of Illinois at Chicago
Chicago, Illinois, 60612
United States

Collaborators and Investigators

Sponsor: University of Illinois at Chicago

  • Robert W Motl, PhD, PRINCIPAL_INVESTIGATOR, University of Illinois Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-01
Study Completion Date2025-03-31

Study Record Updates

Study Start Date2023-04-01
Study Completion Date2025-03-31

Terms related to this study

Keywords Provided by Researchers

  • Multiple Sclerosis
  • MS
  • Depression
  • MDD
  • Exercise
  • Physical Activity
  • Intervention
  • Behavior

Additional Relevant MeSH Terms

  • Multiple Sclerosis
  • Major Depressive Disorder