RECRUITING

Amygdala Memory Enhancement

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.

Official Title

Mechanisms of Amygdala-Mediated Memory Enhancement in Humans

Quick Facts

Study Start:2021-11-01
Study Completion:2027-11-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05065450

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Must be able to understand and speak English.
  2. * Able to provide informed consent.
  3. * Diagnosed with epilepsy.
  4. * Scheduled to undergo long-term intra-cranial video monitoring for seizure onset localization.
  5. * Must be implanted with intracranial depth electrodes to the left or right amygdala, hippocampus, and parahippocampal/perirhinal cortices.
  1. * Unable to understand and speak English.
  2. * Unable to provide informed consent.
  3. * Not diagnosed with epilepsy.

Contacts and Locations

Study Contact

Joan Atencio
CONTACT
314-362-3114
atencio@wustl.edu
Sophie Church
CONTACT
917-699-9097
sophie.church@wustl.edu

Study Locations (Sites)

Washington University School of Medicine
Saint Louis, Missouri, 63110
United States

Collaborators and Investigators

Sponsor: Washington University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-11-01
Study Completion Date2027-11-01

Study Record Updates

Study Start Date2021-11-01
Study Completion Date2027-11-01

Terms related to this study

Additional Relevant MeSH Terms

  • Brain Diseases
  • Epilepsy
  • Memory Disorders
  • Traumatic Brain Injury
  • Cognitive Impairment
  • Post Traumatic Stress Disorder