RECRUITING

Augmenting Ankle Plantarflexor Function in Cerebral Palsy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The first specific aim is to quantify improvement in ankle muscle function and functional mobility following targeted ankle resistance gait training in ambulatory children with cerebral palsy (CP). The primary hypothesis for the first aim is that targeted ankle resistance training will produce larger improvements in lower-extremity motor control, gait mechanics, and clinical measures of mobility assessed four- and twelve-weeks post intervention compared to standard physical therapy and standard gait training. The second specific aim is to determine the efficacy of adaptive ankle assistance to improve capacity and performance during sustained, high-intensity, and challenging tasks in ambulatory children with CP. The primary hypothesis for the second aim is that adaptive ankle assistance will result in significantly greater capacity and performance during the six-minute-walk-test and graded treadmill and stair stepping protocols compared to walking with ankle foot orthoses and walking with just shoes.

Official Title

Augmenting Ankle Plantarflexor Function and Walking Capacity in Children With Cerebral Palsy

Quick Facts

Study Start:2023-02-01
Study Completion:2026-09-25
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05154253

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:8 Years to 21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages between 8 and 21 years old, inclusive. Diagnosis of CP and a pathological gait pattern caused by ankle dysfunction.
  2. * Able to understand and follow simple directions (based on parent report, if needed) and walk at least 30 feet with or without a walking aid (Gross Motor Function Classification System (GMFCS) Level I-III).
  3. * At least 20° of passive plantar-flexion range of motion.
  1. * Concurrent treatment other than those assigned during the study.
  2. * A condition other than CP that would affect safe participation.
  3. * Surgical intervention within 6 months of participation.

Contacts and Locations

Study Contact

Zach Lerner, PhD
CONTACT
928-523-1787
zachary.lerner@nau.edu

Principal Investigator

Zach F Lerner, PhD
PRINCIPAL_INVESTIGATOR
Northern Arizona University

Study Locations (Sites)

Gillette Children's Specialty Healthcare
Minneapolis, Minnesota, 55101
United States

Collaborators and Investigators

Sponsor: Northern Arizona University

  • Zach F Lerner, PhD, PRINCIPAL_INVESTIGATOR, Northern Arizona University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-01
Study Completion Date2026-09-25

Study Record Updates

Study Start Date2023-02-01
Study Completion Date2026-09-25

Terms related to this study

Keywords Provided by Researchers

  • Gait
  • Rehabilitation

Additional Relevant MeSH Terms

  • Cerebral Palsy