RECRUITING

Medication Adherence Program

Description

Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive medication adherence, blood pressure control, and quality of life. Participants (n=402) \>=40 years old with a diagnosis of hypertension, uncontrolled blood pressure, and low antihypertensive medication adherence will be recruited through a statewide health insurer, Blue Cross Blue Shield of Louisiana, and randomized to receive either interactive health coaching sessions with medication reminder tools (intervention) or medication reminder tools only (control) over one year. Data will be collected from participants at baseline, 6 months, 12 months, and 24 months using questionnaires, physical measurement (height, weight, blood pressure), a computer-based single-category implicit association test, and laboratory analysis of antihypertensive medication urinary metabolites.

Study Overview

Study Details

Study overview

Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive medication adherence, blood pressure control, and quality of life. Participants (n=402) \>=40 years old with a diagnosis of hypertension, uncontrolled blood pressure, and low antihypertensive medication adherence will be recruited through a statewide health insurer, Blue Cross Blue Shield of Louisiana, and randomized to receive either interactive health coaching sessions with medication reminder tools (intervention) or medication reminder tools only (control) over one year. Data will be collected from participants at baseline, 6 months, 12 months, and 24 months using questionnaires, physical measurement (height, weight, blood pressure), a computer-based single-category implicit association test, and laboratory analysis of antihypertensive medication urinary metabolites.

Supporting Tailored Adaptive Change and Reinforcement for Medication Adherence Program: Randomized Trial of a Novel Approach to Improve Adherence in Older Hypertensive Women and Men

Medication Adherence Program

Condition
Hypertension
Intervention / Treatment

-

Contacts and Locations

Baton Rouge

Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States, 70808

Covington

Tulane Doctors Dermatology & Multispecialty Clinic, Covington, Louisiana, United States, 70433

Metairie

Tulane Doctors Heart & Vascular and Primary Care Clinic, Metairie, Louisiana, United States, 70002

New Orleans

Tulane University Clinical and Translational Unit, New Orleans, Louisiana, United States, 70112

Shreveport

LSU Health Sciences Shreveport Clinical Trials Office, Shreveport, Louisiana, United States, 71101

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * fully insured by Blue Cross Blue Shield of Louisiana (BCBSLA)
  • * continuously enrolled in BCBSLA for one year
  • * planning to remain a member of BCBSLA for next year
  • * English-speaking
  • * telephone access
  • * aged ≥40 years
  • * diagnosis of essential hypertension (ICD-10-CM code I10)
  • * currently filling antihypertensive medication
  • * low antihypertensive medication refill (proportion of days covered (PDC) \<0.8)
  • * low self-report adherence (4-item Krousel-Wood Medication Adherence Scale (K-Wood-MAS-4) score ≥1)
  • * uncontrolled blood pressure (BP) (systolic BP ≥130 mm Hg or diastolic BP ≥80 mm Hg)
  • * desire to improve BP
  • * living in a household with someone already enrolled in the study
  • * enrollment in another clinical trial for drug adherence or BP control
  • * moderate to severe cognitive impairment

Ages Eligible for Study

40 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Tulane University,

Marie A Krousel-Wood, MD, MSPH, PRINCIPAL_INVESTIGATOR, Tulane University

Study Record Dates

2027-04-30