RECRUITING

The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.

Official Title

The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

Quick Facts

Study Start:2022-04-01
Study Completion:2026-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05254431

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of COPD and OSA, i.e., Overlap Syndrome Diagnosis of Overlap Syndrome (both COPD and OSA), confirmed in CPRS from spirometry or pulmonary function test of FEV1/FVC \<70 for COPD and a polysomnogram or home-based study for OSA.
  2. * Montreal Cognitive Assessment (MoCA) \>20
  1. * CAD, as defined by anyone of the following: history of CABG, prior positive stress test for ischemia, infarction or angina or medical problem
  2. * Orthopedic problems as defined by joint pain limiting ambulation
  3. * Fall risk, defined as more than 2 falls in the prior month
  4. * Hospitalization in prior month
  5. * Daytime home oxygen 6. Participation in structured exercise, defined by the Physical Activity Scale for the Elderly (PASE) as more than 1 hour of activity spent in moderate activity and any strenuous activity performed over prior 7 days.

Contacts and Locations

Study Contact

Tracy A Hicks
CONTACT
(540) 982-2463
Tracy.Hicks2@va.gov
Donna J Arsura
CONTACT
(540) 982-2463
donna.arsura@va.gov

Principal Investigator

Madalina Macrea, MD PhD
PRINCIPAL_INVESTIGATOR
Salem VA Medical Center, Salem, VA

Study Locations (Sites)

Salem VA Medical Center, Salem, VA
Salem, Virginia, 24153-6404
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Madalina Macrea, MD PhD, PRINCIPAL_INVESTIGATOR, Salem VA Medical Center, Salem, VA

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-01
Study Completion Date2026-04-01

Study Record Updates

Study Start Date2022-04-01
Study Completion Date2026-04-01

Terms related to this study

Keywords Provided by Researchers

  • COPD
  • OSA
  • Overlap Syndrome

Additional Relevant MeSH Terms

  • COPD
  • OSA