RECRUITING

Neuroimaging Reveals Treatment-related Changes in DLD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.

Official Title

Neuroimaging Reveals Treatment-related Changes in DLD

Quick Facts

Study Start:2022-05-24
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05268341

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:48 Months to 71 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * ages 48-71 months
  2. * average nonverbal intelligence quotient (IQ)
  3. * enrolled in participating center
  4. * typically developing (receptive and expressive language, social, articulation, other)
  5. * DLD for expressive grammar
  6. * typical oral motor function
  7. * typical social/pragmatics skills
  8. * average hearing thresholds
  9. * monolingual and native Standard English speakers
  10. * does not have any uncorrected vision challenges
  1. * receiving co-occurring speech-language or other intervention for communication
  2. * not MRI safe
  3. * special education placement of child based on ability or behavior

Contacts and Locations

Study Contact

Karla N Washington, PhD
CONTACT
513-558-8533
washink2@ucmail.uc.edu
Jennifer J Vannest, PhD
CONTACT
513-558-8518
vannesjr@ucmail.uc.edu

Principal Investigator

Karla N Washington, PhD
PRINCIPAL_INVESTIGATOR
University of Cincinnati

Study Locations (Sites)

New Horizon Childcare
Cincinnati, Ohio, 45207
United States
Empower Learn Create INC
Cincinnati, Ohio, 45220
United States
Cincinnati Children's Hospital
Cincinnati, Ohio, 45229
United States
CWFF CHild Development Center
Cincinnati, Ohio, 45229
United States
Wesley Education Center for Children and Families
Cincinnati, Ohio, 45229
United States
University of Cincinnati
Cincinnati, Ohio, 45267
United States

Collaborators and Investigators

Sponsor: University of Cincinnati

  • Karla N Washington, PhD, PRINCIPAL_INVESTIGATOR, University of Cincinnati

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-05-24
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2022-05-24
Study Completion Date2026-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Developmental Language Disorder