RECRUITING

Pistachios and Neural Macular Pigment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss as people age. Studies have shown that lutein and zeaxanthin, nutrients found in green leafy vegetables and egg yolks, can help protect against AMD in older adults. These nutrients form a pigment in the retina (macular pigment) that can help protect the retina from light damage. Pistachios are rich sources of both lutein and zeaxanthin; thus, dietary intake of pistachios could serve as a beneficial food source for eye health.

Official Title

Pistachios and Neural Macular Pigment; a Randomized Controlled Trial

Quick Facts

Study Start:2022-06-10
Study Completion:2023-11-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05283941

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Adult men and women, aged 40 - 70 years
  2. 2. Body Mass Index (BMI): 20.0 - 36.9 kg/m2
  3. 3. Low macular pigment density at baseline (\<0.5 OD)
  4. 4. Low lutein and zeaxanthin intake at baseline (\<2 mg/d)
  1. 1. Inability to perform the heteroflicker photometry procedures with or without corrective lenses (i.e. glasses or contact lenses) during in-house screening.
  2. 2. History of (self-reported):
  3. * Fat malabsorption
  4. * Use of drugs that interfere with fat absorption or metabolism
  5. * Tree nut allergy
  6. * Eye disease, including macular degeneration and cataracts
  7. * Small bowel disease or resection
  8. * Atrophic gastritis
  9. * Hyperlipidemia
  10. * Insulin-requiring diabetes
  11. * \> 14 alcoholic drinks per week
  12. * Pancreatic disease
  13. * Bleeding disorders
  14. * Pregnancy (or hoping to become pregnant during participation in the study)
  15. * Carotenoid or fatty acid dietary supplements within 2 months of the study
  16. * Non-English speaker
  17. * Any condition that would make it unlikely that the participant would be able to complete the requirements of the study.

Contacts and Locations

Study Contact

Tammy Scott, PhD
CONTACT
617-962-1496
tammy.scott@tufts.edu

Principal Investigator

Tammy Scott
PRINCIPAL_INVESTIGATOR
Tufts University

Study Locations (Sites)

Clinical and Translational Research Center (CTRC) - Tufts
Boston, Massachusetts, 02111
United States

Collaborators and Investigators

Sponsor: Tufts University

  • Tammy Scott, PRINCIPAL_INVESTIGATOR, Tufts University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-10
Study Completion Date2023-11-30

Study Record Updates

Study Start Date2022-06-10
Study Completion Date2023-11-30

Terms related to this study

Keywords Provided by Researchers

  • age related macular degeneration
  • lutein
  • zeaxanthin
  • pistachios
  • macular pigment
  • AMD

Additional Relevant MeSH Terms

  • Macular Degeneration
  • Retinal Degeneration
  • Retinal Diseases
  • Eye Diseases