ACTIVE_NOT_RECRUITING

Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase III trial investigates if perflutren lipid microspheres with ultrasound can be used to diagnose prostate cancer non-invasively. Definity (perflutren lipid microspheres) is an ultrasound contrast agent that is typically used for ultrasound bubble studies that involve the heart. Definity appears on ultrasound images as tiny gas-filled microbubbles. These microbubbles are about the size of a red blood cell and do not stay in a patient's body for more than several minutes, where they are excreted from the lungs and exhaled back into the air when breathing. Definity may enhance ultrasound images of the prostate and help doctors identify prostate cancer on ultrasound images.

Official Title

Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)

Quick Facts

Study Start:2022-06-15
Study Completion:2026-05-26
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05336786

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subject must be scheduled for radical prostatectomy for treatment of prostate cancer
  2. * Subject must be able and willing to give written informed consent for a contrast enhanced ultrasound study of the prostate prior to prostatectomy
  3. * Subject must be a male at least 18 years of age when informed consent is obtained
  1. * Participant in a clinical trial involving an investigational drug within the past 30 days
  2. * Patients with known or suspected hypersensitivity to perflutren, PEG, or any other component of Definity
  3. * Previous treatment for prostate cancer, including hormone therapy
  4. * Clinically unstable, severely ill, or moribund as per treating physician

Contacts and Locations

Study Locations (Sites)

Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107
United States

Collaborators and Investigators

Sponsor: Thomas Jefferson University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-15
Study Completion Date2026-05-26

Study Record Updates

Study Start Date2022-06-15
Study Completion Date2026-05-26

Terms related to this study

Additional Relevant MeSH Terms

  • Prostate Carcinoma