RECRUITING

Prandial Metabolic Phenotype in Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Previous studies suggest that changes in metabolism due to the effects of aging might serve as a potential for therapeutic agents. The investigating lab developed a pulse method combining multiple stable isotopes to study multiple metabolic pathways in the same individual simultaneously. By measuring whole-body metabolism in a large group of older adults, the investigators may be able to unravel age-related deterioration in protein turnover (synthesis and breakdown) that contributes to impaired functional capacity. Metabolic profiles could explain differences in pathways in the aging process with special interest in metabolism of amino acids as they have been associated with aging-related disorders.

Official Title

Prandial Metabolic Phenotype in Adults

Quick Facts

Study Start:2022-06-24
Study Completion:2025-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05400733

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age: 60-80, inclusive
  2. * Stable body-weight (± 5%) for the past 3 months
  3. * Subject is judged to be in satisfactory health based on medical history, physical examination, and laboratory screening evaluations.
  4. * Ability to walk, sit down and stand up independently or with walking mobility aids
  5. * Ability to lie in supine or elevated position for up to 7 hours
  6. * Willingness and ability to comply with the protocol
  1. * Established diagnosis of current malignancy
  2. * History of untreated metabolic diseases including hepatic or renal disorder
  3. * Presence of acute illness or metabolically unstable chronic illness
  4. * Presence of fever within the last 3 days
  5. * Use of short course of oral corticosteroids within 4 weeks preceding study day
  6. * (Possible) pregnancy
  7. * Failure to give informed consent or Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
  8. * Already enrolled in another clinical trial and that clinical trial interferes with participating in this study
  9. * Any other condition according to the PI or nurse that was found during the screening visit, that would interfere with the study or safety of the patient

Contacts and Locations

Study Contact

Marielle Engelen
CONTACT
9792202282
mpkj.engelen@ctral.org
Savanah Knezek
CONTACT
9793186010
s.knezek@ctral.org

Study Locations (Sites)

Human Clinical Research Facility
College Station, Texas, 77843
United States

Collaborators and Investigators

Sponsor: Texas A&M University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-24
Study Completion Date2025-04

Study Record Updates

Study Start Date2022-06-24
Study Completion Date2025-04

Terms related to this study

Keywords Provided by Researchers

  • prandial

Additional Relevant MeSH Terms

  • Protein Metabolism