ACTIVE_NOT_RECRUITING

A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer. Most children with leukemia and lymphoblastic lymphoma can be cured due to advancements in diagnosis and treatment. However, because treatments for these conditions target the central nervous system, these children are at increased risk for developing neurocognitive late effects (problems with attention, thinking, learning, and remembering). Fortunately, many survivors do well, but some children continue to struggle with learning and have academic difficulties after their cancer treatments. The purpose of this research study is to see whether providing parents with educational knowledge and parenting tips using videoconferencing and a special website better helps their cancer survivor child in learning and school achievement compared to typical services.

Official Title

Leveraging Digital Health Solutions to Reduce Learning and Functional Disparities in Children With Cancer

Quick Facts

Study Start:2023-02-16
Study Completion:2027-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05428176

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:6 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Documented informed consent of the participant and/or legally authorized representative
  2. * Assent, when appropriate, will be obtained per institutional guidelines
  3. * Primary participating parent/caregiver is English- or Spanish-speaking (any race/ethnicity)
  4. * Child is aged 6-12 years (yr.) (for the website usability pre-study, child is age 8 - 12 yrs.)
  5. * Child understands English (but can be bilingual)
  6. * Child treated for acute leukemia (e.g., acute lymphoblastic leukemia, acute myelogenous leukemia) or lymphoblastic lymphoma
  7. * Child is in cancer remission and has completed cancer therapies, including maintenance treatment
  8. * Primary participating parent/caregiver has daily contact with the child
  9. * Child is enrolled in school
  1. * Recent or current participation in a behavioral intervention study with a similar focus
  2. * History of major psychiatric condition (e.g., psychosis) in parent or child
  3. * Severe neurodevelopmental disorder in the child (e.g., down syndrome, intellectual disability)
  4. * Child has previously used the IXL online learning program extensively and unwilling to regularly use it again
  5. * Any other condition that would, in the investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures
  6. * Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)

Contacts and Locations

Principal Investigator

Sunita K Patel
PRINCIPAL_INVESTIGATOR
City of Hope Medical Center

Study Locations (Sites)

City of Hope Medical Center
Duarte, California, 91010
United States
Childrens Hospital of Los Angeles
Los Angeles, California, 90027
United States
Rady Children's Hospital San Diego
San Diego, California, 92123
United States
University of Calif San Francisco
San Francisco, California, 94115
United States

Collaborators and Investigators

Sponsor: City of Hope Medical Center

  • Sunita K Patel, PRINCIPAL_INVESTIGATOR, City of Hope Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-16
Study Completion Date2027-06-30

Study Record Updates

Study Start Date2023-02-16
Study Completion Date2027-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Acute Leukemia
  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Lymphoblastic Lymphoma