ACTIVE_NOT_RECRUITING

Influenza IMPRINT Cohort: Defining the Impact of Initial Influenza Exposure on Immunity in Infants

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary aim is to define the immune responses to the infant's initial influenza exposure (vaccine or infection) and how that affects the immune response to subsequent influenza exposures

Official Title

Influenza IMPRINT Cohort: Defining the Impact of Initial Influenza Exposure on Immunity in Infants

Quick Facts

Study Start:2019-10-17

Study Completion:2028-12-31

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05436184

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:CHILD, ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Mother pregnant and ≥ 34 weeks gestation and ≥ 18 yrs. of age * Plans to deliver at local hospital * Lives within designated home zip codes: * No plans to move outside study area within study timeframe * Cell phone that can be used for text messaging * Singleton live born infant, born ≥ 34 weeks gestational age (GA)	* Fetal or infant death prior to maternal hospital discharge * Mother known to be infected with HIV based on medical records * Major congenital anomalies, prenatally diagnosed or other major disorder or anomaly as determined by the PI * Reported use of heroin, cocaine or methamphetamines during pregnancy * Adoptive infant * Enrolled in any investigational vaccine trial or other interventional randomized, clinical trial involving the mother or infant that the PI's deem to be in conflict with study outcomes

Inclusion Criteria

Exclusion Criteria

* Mother pregnant and ≥ 34 weeks gestation and ≥ 18 yrs. of age
* Plans to deliver at local hospital
* Lives within designated home zip codes:
* No plans to move outside study area within study timeframe
* Cell phone that can be used for text messaging
* Singleton live born infant, born ≥ 34 weeks gestational age (GA)

* Fetal or infant death prior to maternal hospital discharge
* Mother known to be infected with HIV based on medical records
* Major congenital anomalies, prenatally diagnosed or other major disorder or anomaly as determined by the PI
* Reported use of heroin, cocaine or methamphetamines during pregnancy
* Adoptive infant
* Enrolled in any investigational vaccine trial or other interventional randomized, clinical trial involving the mother or infant that the PI's deem to be in conflict with study outcomes

Contacts and Locations

Principal Investigator

Mary Staat, MD,MPH

PRINCIPAL_INVESTIGATOR

Children's Hospital Medical Center, Cincinnati

Study Locations (Sites)

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45219

United States

Collaborators and Investigators

Sponsor: Children's Hospital Medical Center, Cincinnati

Mary Staat, MD,MPH, PRINCIPAL_INVESTIGATOR, Children's Hospital Medical Center, Cincinnati

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-10-17

Study Completion Date2028-12-31

Study Record Updates

Study Start Date2019-10-17

Study Completion Date2028-12-31

Terms related to this study

Keywords Provided by Researchers

influenza, birth cohort

Additional Relevant MeSH Terms

Influenza