ACTIVE_NOT_RECRUITING

Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward grading scale based on visual and tactile information readily available during RFA procedures as part of routine practice (per radiofrequency electrode: 0 = no twitches palpated or observed; 1 = twitches palpated but not observed; 2 = twitches palpated and observed at 1-2 levels; 3= twitches palpated and observed at \>2 levels). If a higher weighted score (total score divided by number of radiofrequency lesion sites) correlates with a greater likelihood of treatment success, or magnitude or duration of analgesia following cervical RFA, cervical paraspinal muscle twitching may serve as a readily obtainable prognostic factor (marker) for effectiveness.

Official Title

The Predictive Value of Cervical Paraspinal Muscle Twitching During Motor Stimulation Testing on Cervical Facet Joint Radiofrequency Ablation Outcomes

Quick Facts

Study Start:2022-09-13
Study Completion:2027-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05450679

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 years or older
  2. * Cervical facet arthropathy based on history and physical exam (e.g. axial cervical neck pain, paraspinal tenderness, no pain referral below the ipsilateral shoulder)
  3. * Radiologic evidence of cervical pathology consistent with symptoms if MRI is available
  4. * Pain duration of greater than 3 months
  5. * Obtained 50% or greater pain relief from at least 1 diagnostic cervical medial branch block of the identical medial branch nerves targeted for RFA
  1. * Untreated coagulopathy
  2. * Signs or symptoms of cervical myelopathy
  3. * Signs or symptoms of cervical radiculitis/radiculopathy
  4. * Allergic reactions to local anesthetics
  5. * Serious psychiatric disorder (e.g. uncontrolled or refractory depression) that might preclude optimal outcome
  6. * Poorly controlled medical condition (e.g. pacemaker that cannot be switched off, unstable angina)
  7. * Pregnancy

Contacts and Locations

Principal Investigator

Eric Wang, MD
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Johns Hopkins Hospital
Baltimore, Maryland, 21287
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Eric Wang, MD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-13
Study Completion Date2027-08-01

Study Record Updates

Study Start Date2022-09-13
Study Completion Date2027-08-01

Terms related to this study

Keywords Provided by Researchers

  • facet arthropathy
  • cervicalgia
  • radiofrequency ablation

Additional Relevant MeSH Terms

  • Cervical Facet Joint Pain
  • Chronic Pain
  • Neck Pain